GMP acceptance of veterinary drugs passed the enterprise 

Veterinary drug GMP Certificate Number: (2022) Veterinary drug GMP Certificate number 15049 

Veterinary Drug Production License: (2022) Veterinary Drug production License No. 15318

Instructions For Toltrazuril Suspension

【Veterinary drug name】 

Product name:  Toltrazuril Suspension

Chinese Pinyin: Tuoguzhuli Hunxuanye

【Main ingredient】Totrizuril

【Characters】This product is self-colored to slightly yellow suspension, standing stratification

【Pharmacological action】This product belongs to triazinone broad-spectrum anti-coccidium drug. Its mechanism of action is to interfere with the nuclear division and mitochondria of coccidium, affect the respiratory and metabolic functions of coccidium, and make the endoplasmic reticulum of cells expand and cause serious void formation, which has a direct killing effect on the developmental stage of the worm body (trophoblast, schizozoite and gametes). Does not affect the production of immunity.

At 120 hours after oral administration, the maximum drug concentration was detected in plasma, and the elimination half-life was 154 hours. The maximum drug concentration was reached 48 hours after oral administration of pigs, and the elimination half-life was 148.2 hours.

【Indication】 For prevention of coccidiosis in piglets and cattle.

【Usage and dosage】 calculated as C18H14F3N3O4S. Orally, a single dose, 15mg per kg body weight for calves: 3~5kgs of piglets aged 3-5 days,20mg per kilogram.

【Adverse reactions】According to the recommended dose, no adverse reactions were observed.

【Cautions】

(1) Shake thoroughly before use :

(2) Do not use this product for cows weighing more than 80kg and fatting cows;

(3) Keep this product away from children and food;

(4) Use this product within three months after opening the lid. 

(5) It is recommended that all calves in the same column should be treated at the same time; 

(6) Other assistance should be given to calves who have diarrhea due to coccidiosis.

(7) The main metabolite of toltrisulfone is toltrisulfone, which is stable "half-life &gt>1 year) and soluble in soil, which is toxic to plants. The faces of cattle after drug use should be diluted with at least 3 times the weight of untreated cattle faces before being excreted into the soil.

【Drug withdrawal period】Calf 63 days, piglets 77 days

【 Specification 】 Calculate 5% according to C18H14F3N3O4S

【 Package 】100ml: 1L

【 Storage 】 Sealed storage

【 Approval number 】

【 Production date 】

【 Batch number 】 

【 Manufacturer】Shandong Dexin Biotechnology Co.ltd